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Test Code CRCL.1 CREATININE CLEARANCE 24 HOUR URINE

Important Note

Include: Height, weight, collection period and total volume. (Required to calculate results.)

Serum should be collected within 24 hours of urine collection start or finish.

Serum specimens should be free of hemolysis.

Optimal urine sample should be free of contaminants including red blood cell contamination.

Serum specimen will be accepted if collected within 7 days of urine collection.

Additional Codes

CREATCLEAR

CRE24

Methodology

Automated Chemistry Analyzer

Specimen Requirements

Serum and 24-hour Urine Collection

Container: SST tube ( or green top) and 24-hour dark plastic urine container

Specimen Collection: 2 mL serum and 40 mL urine (minimum 0.2 mL serum and 1 mL urine)

  1. Collect a 24-hour urine in a 24-hour dark plastic urine container. Refrigerate during collection. Urine may be collected with 25 - 30 mL of Hydrochloric acid.
  2. Allow specimen to clot completely if  a serum tube (SST) was used.
  3. Separate serum (SST) or plasma (Lithium Heparin) from cells within 24 hours and transport refrigerated. If red top tube is collected, separate serum from cells within 2 hours and place in separate plastic tube.
  4. Properly label tube with patient's name, DOB, requisition number and type of tube, i.e. GREEN.
  5. Aliquot 40 mL of a well-mixed 24-hour urine collection into a leakproof plastic urine container.
  6. Record collection time and total volume.
  7. Store and transport both specimens refrigerated.

Alternate Specimens: Lithium heparin plasma (green top) and urines preserved in the boric acid tubes (BD C&S tubes.)

Specimen Transport/Stability

Refrigerated: 24 hours on gel, 7 days poured off

Maximum Laboratory Time

24 to 48 hours

Reference Ranges

 

Height in
Weight lbs
Collection Period h
Volume mL
Creatinine mg/dL
Newborn 0.20 - 0.99
3 days 0.20 - 0.50 
2 yrs 0.20 - 0.60
4 yrs 0.20 - 0.70 
8 yrs 0.30 - 0.80 
11 yrs  0.30 - 0.90
13 yrs 0.30 - 1.10
18 yrs F 0.44 - 1.00
18 yrs M 0.61 - 1.24
Creatinine, Urine  mg/dL
  80.00 - 170.00
Creatinine Clearance mL/min
Female 88.0 - 128.0 
Male 97.0 - 137.0

 

 

 

 

Day(s) Test Set Up

Daily

Test Classification and CPT Coding

82575