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HelpTest Code CIFS Cutaneous Immunofluorescence Antibodies, IgG and IgG4, Serum
Reporting Name
Cutaneous Immfluor. Ab, IgG/IgG4, SUseful For
Confirming the presence of IgG and/or IgG4 antibodies to diagnose pemphigoid, pemphigus, epidermolysis bullosa acquisita, or bullous lupus erythematosus
Method Name
Indirect Immunofluorescence Assay (IFA)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Collection Container/Tube:
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 14 days |
Reference Values
Negative in normal individuals
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
88346
88350
88350 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CIFS | Cutaneous Immfluor. Ab, IgG/IgG4, S | In Process |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 21539 | Cell Surface Ab IgG | 93233-5 |
| 21540 | Basement Membrane IgG | 29994-1 |
| 21542 | Primate Split Skin IgG | 104832-1 |
| 622319 | Cell Surface Ab IgG4 | In Process |
| 622320 | Basement Membrane IgG4 | In Process |
| 622322 | Primate Split Skin IgG4 | In Process |
| 21638 | Other | 48767-8 |
Report Available
2 to 7 daysSecondary ID
8052Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| CIFST | CIFS Titer, IgG, S | No | No |
Testing Algorithm
If IgG anti-cell surface or anti-basement membrane zone antibodies are present, then the IgG antibody titer will be reflexed and performed at an additional charge.