Test Code CHIKS Chikungunya Virus, PCR, Molecular Detection, Serum
Reporting Name
Chikungunya Virus, PCR, SerumUseful For
Qualitative detection of chikungunya virus in serum after early symptom onset (ideally <7 days)
This test is not recommended for screening healthy patients.
Method Name
Real-Time Reverse Transcription Polymerase Chain Reaction (PCR)/DNA Probe Hybridization
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumAdditional Testing Requirements
Due to the short period in which chikungunya RNA may be detected in serum, testing serum for IgM- and IgG-class antibodies to chikungunya virus is also recommended. See CHIKV / Chikungunya IgM and IgG, Antibody, Serum.
Testing for RNA or IgM-class antibodies to dengue and Zika viruses, concurrently with chikungunya virus testing should also be considered, given the overlapping clinical syndromes seen with these viruses.
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container: Sterile container
Specimen Volume: 0.5 mL
Collection Instructions:
1. Within 2 hours of collection, centrifuge and aliquot the serum into a sterile container.
2. Serum specimens not aliquoted from the serum gel collection tube into a sterile container will be rejected.
Reject Due To
| Gross hemolysis | Reject |
| Heat-inactivated specimen | Reject |
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 7 days |
Reference Values
Negative
Reference values apply to all ages.
Day(s) Performed
Monday, Wednesday, Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
87798
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| CHIKS | Chikungunya Virus, PCR, Serum | 81152-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 603833 | Chikungunya Virus, PCR, Serum | 81152-1 |
Secondary ID
603833Report Available
Same day/1 to 5 daysTesting Algorithm
For more information see Mosquito-borne Disease Laboratory Testing.
Special Instructions
Forms
If not ordering electronically, complete, print, and send a Microbiology Test Request (T244) with the specimen.